Maternal Residential Proximity to Air Emissions from Industrial Facilities and Low Birth Weight in Offspring in Texas: A Case-Control Study

Authors: Xi Gong*, University of New Mexico, F. Benjamin Zhan, Texas State University
Topics: Medical and Health Geography, Geographic Information Science and Systems, Spatial Analysis & Modeling
Keywords: air pollution, toxic release inventory (TRI) chemicals, low birth weight (LBW), exposure assessment, Emission Weighted Proximity Model (EWPM), GIS, spatial modeling, health
Session Type: Paper
Day: 4/12/2018
Start / End Time: 10:00 AM / 11:40 AM
Room: Studio 6, Marriott, 2nd Floor
Presentation File: No File Uploaded


Many studies have investigated association between maternal exposures to criteria air pollutants (PM2.5, PM10, O3, NO2, SO2, CO, and Pb) and low birth weight (LBW). However, only a few studies examined the potential impact of other air pollutants on LBW. Based on a dataset with 94,106 LBW cases and 376,424 controls in Texas from 1996 to 2008, this study investigated associations between maternal residential exposure to industrial air emissions of 449 Toxics Release Inventory (TRI) chemicals and LBW in offspring. Maternal residential exposure to chemicals was estimated using a modified Emission Weighted Proximity Model. Binary logistic regression was used to compute odds ratios reflecting the association for a Chemical-LBW combination. The odds ratios were adjusted for birth year, public health region, child’s sex, gestational length, maternal age, education, and race/ethnicity. Relative to exposure intensities of zero, LBW was associated with maternal residential exposures (exposure intensities >0) to several types of chemicals, most notably acetamide (adjusted odds ratio [aOR] 1.60, 95% confidence interval [CI] 1.09, 2.34), p-phenylenediamine (aOR 1.32, CI 1.07,1.63), 2,2-dichloro-1,1,1-trifluoroethane (aOR 1.21, CI 1.10, 1.34), 1,2-phenylenediamine (aOR 1.20, CI 1.02, 1.41), resmethrin (aOR 1.14, CI 1.01, 1.30), toluene 2,6-diisocyanate (aOR 1.14, CI 1.02, 1.28), tributyltin methacrylate (aOR 1.14, CI 1.05, 1.23), propetamphos (aOR 1.11, CI 1.01, 1.23), 1,1,1-trichloroethane (aOR 1.10, CI 1.05, 1.15), and creosote (aOR 1.09, CI 1.02, 1.16). The results suggest that maternal residential proximity to industrial facilities with emissions of some chemicals may be associated with LBW in offspring.

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